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  Indian J Med Microbiol
 

Figure 2: The schematic mapping for each row of Jacobian and sensitivity matrices on the mesh space. The Jacobian matrix has the row numbers equivalent to the number of source-detector pairs. The columns number of the Jacobian matrix is equivalent to the number of points defined for the sample simulation (the number of mesh nodes). The number of each element indicates the sensitivity of the corresponding point (the change in the intensity received by the detector for the changed optical characteristics in each point) in the imaging system. If there are a source and one detector around the source, the imaging sensitivity could be seen in the form of a banana in the sample space, which is a row of the Jacobian matrix overlaid on the sample. The sensitivity matrix (sj) is calculated based on the raw summation of the Jacobian matrix

Figure 2: The schematic mapping for each row of Jacobian and sensitivity matrices on the mesh space. The Jacobian matrix has the row numbers equivalent to the number of source-detector pairs. The columns number of the Jacobian matrix is equivalent to the number of points defined for the sample simulation (the number of mesh nodes). The number of each element indicates the sensitivity of the corresponding point (the change in the intensity received by the detector for the changed optical characteristics in each point) in the imaging system. If there are a source and one detector around the source, the imaging sensitivity could be seen in the form of a banana in the sample space, which is a row of the Jacobian matrix overlaid on the sample. The sensitivity matrix (s<sub>j</sub>) is calculated based on the raw summation of the Jacobian matrix